Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593885 | 0.87 | ALDH1A1 (0.39) | SMN1; SMN2LOXLOXL2PDE10AALDH1A1 | |
| SCHEMBL26627240 | 0.82 | ESR1 (0.36) | FAAHLMNAHSP90AB1 | |
| SCHEMBL17169789 | 0.81 | SMN1; SMN2 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| Hydrochloric Acid SCHEMBL7451596 | 0.79 | SMN1; SMN2 (0.38) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| SCHEMBL13990856 | 0.79 | SMN1; SMN2 (0.41) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| SCHEMBL24434490 | 0.79 | S1PR1 (0.33) | FAAHMGLLSMN1; SMN2LOXLOXL2 | |
| SCHEMBL12988241 | 0.78 | GRM5 (0.35) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| SCHEMBL29879916 | 0.78 | RECQL (0.41) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| SCHEMBL5897930 | 0.78 | SMN1; SMN2 (0.37) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX | |
| SCHEMBL2541070 | 0.78 | RECQL (0.41) | TAS1R3TAS1R1TAS1R2SMN1; SMN2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | ACADEMY OF MILITARY MEDICAL SCIENCES (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022033303-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303494-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | CD274, PDCD1, PDCD1LG2 | TAS1R3 3236/4885TAS1R1 1709/4885TAS1R2 3244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.