Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056124 | 0.94 | MAPT (0.50) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL24253057 | 0.84 | HSD17B10 (0.46) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL22918166 | 0.84 | ERN1 (0.48) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1539204 | 0.84 | SMN1; SMN2 (0.52) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL590803 | 0.83 | SMN1; SMN2 (0.50) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL26075664 | 0.83 | CCNB2 (0.46) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL187045 | 0.83 | MAPT (0.60) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL24253040 | 0.82 | PDCD1 (0.55) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL18209408 | 0.82 | MAPT (0.47) | MAPTL3MBTL1SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31588911 | 0.82 | MAPT (0.66) | MAPTL3MBTL1SMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4198017-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Academy of Military Medical Sciences (CN) | 2023-06-21 | — | — | EP | disclosed |
| WO-2022033303-A1 | BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 中国人民解放军军事科学院军事医学研究院 | 2022-02-17 | — | — | WO | disclosed |