Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.41 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19172142 | 1.00 | DHODH (0.51) | DHODHCYP19A1CYP11B1PIK3CACYP17A1 | |
| SCHEMBL19171480 | 0.97 | CYP19A1 (0.53) | DHODHCYP19A1CYP11B1PIK3CACYP17A1 | |
| SCHEMBL19172223 | 0.96 | DHODH (0.50) | DHODHCYP19A1CYP11B1PIK3CACYP17A1 | |
| SCHEMBL19172127 | 0.96 | DHODH (0.50) | DHODHCYP19A1CYP11B1PIK3CACYP17A1 | |
| SCHEMBL19172267 | 0.96 | DHODH (0.54) | DHODHCYP19A1CYP11B1CYP17A1CYP11B2 | |
| SCHEMBL19172062 | 0.94 | CYP19A1 (0.49) | DHODHCYP19A1CYP11B1PIK3CACYP17A1 | |
| SCHEMBL19167509 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP17A1CYP11B2 | |
| SCHEMBL24252551 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP17A1CYP11B2 | |
| SCHEMBL19172132 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP17A1CYP11B2 | |
| SCHEMBL19172114 | 0.94 | DHODH (0.56) | DHODHCYP19A1CYP11B1CYP17A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220052268-A1 | COMPOUND HAVING PYRIMIDINE RING STRUCTURE AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLC29A1, NUDT1, SLC29A2 | DHODH 202/4885CYP19A1 2810/4885CYP11B1 4052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.