⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252763 | 0.85 | PDE10A (0.35) | — | |
| Formic Acid SCHEMBL25266784 | 0.81 | PDE10A (0.33) | — | |
| Formic Acid SCHEMBL30467756 | 0.81 | PDE10A (0.33) | — | |
| SCHEMBL24252973 | 0.80 | — | — | |
| SCHEMBL26771381 | 0.78 | PDE10A (0.35) | — | |
| SCHEMBL30467566 | 0.75 | PDE10A (0.38) | — | |
| SCHEMBL24252687 | 0.75 | PDE10A (0.38) | — | |
| SCHEMBL24252639 | 0.74 | PDE10A (0.33) | — | |
| SCHEMBL25217989 | 0.74 | PDE10A (0.32) | — | |
| SCHEMBL26779441 | 0.73 | LRRK2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |