Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 19/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.39 |
| ▸ | MAP2K6 | P52564 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.39 |
| ▸ | NEK10 | Q6ZWH5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252729 | 0.77 | PDE10A (0.30) | — | |
| Formic Acid SCHEMBL25232377 | 0.75 | — | — | |
| SCHEMBL24252681 | 0.73 | — | — | |
| SCHEMBL9496321 | 0.67 | LCK (0.77) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL26067975 | 0.61 | LRRK2 (0.40) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL14059836 | 0.61 | LRRK2 (1.00) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL14059982 | 0.60 | LRRK2 (1.00) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL14059741 | 0.60 | LRRK2 (1.00) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL26067972 | 0.60 | LRRK2 (0.37) | LRRK2LCKMAP2K3MAP2K6BTK | |
| SCHEMBL5810397 | 0.60 | LCK (0.40) | LRRK2LCKMAP2K3MAP2K6BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | LRRK2 1477/4885LCK 1883/4885MAP2K3 4360/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | LRRK2 1477/4885LCK 1883/4885MAP2K3 4360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.