Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 1/20 | 0.30 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235915 | 0.93 | PDGFRB (0.32) | PDGFRBKDRNCF1 | |
| Trifluoroacetic Acid SCHEMBL30467727 | 0.92 | F2 (0.35) | PDGFRBKDR | |
| SCHEMBL24252272 | 0.86 | CSF1R (0.40) | PDGFRBKDR | |
| Trifluoroacetic Acid SCHEMBL30467711 | 0.85 | F2 (0.35) | PDGFRBKDR | |
| SCHEMBL25242130 | 0.81 | DHFR (0.33) | PDGFRBKDRALOX5APFEN1 | |
| SCHEMBL25209984 | 0.81 | DHFR (0.33) | PDGFRBKDRALOX5APFEN1 | |
| SCHEMBL26771970 | 0.81 | DHFR (0.33) | PDGFRBKDRALOX5APFEN1 | |
| Trifluoroacetic Acid SCHEMBL30467592 | 0.78 | F2 (0.40) | PDGFRBKDR | |
| Trifluoroacetic Acid SCHEMBL30467745 | 0.75 | F2 (0.35) | PDGFRBKDR | |
| Trifluoroacetic Acid SCHEMBL30467715 | 0.75 | F2 (0.35) | PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2024-04-04 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| EP-4185592-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | Annexon, Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109920-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | PDGFRB 1234/4885KDR 3397/4885ALOX5AP 246/4885 |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | PDGFRB 1234/4885KDR 3397/4885ALOX5AP 246/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | PDGFRB 1234/4885KDR 3397/4885ALOX5AP 246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.