Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | GAK | O14976 | 2/20 | 0.54 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.54 |
| ▸ | COQ8A | Q8NI60 | 2/20 | 0.54 |
| ▸ | NLK | Q9UBE8 | 2/20 | 0.54 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.54 |
| ▸ | STK16 | O75716 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.54 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.53 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 10/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL25214218 | 0.94 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BGAK | |
| Formic Acid SCHEMBL30452291 | 0.94 | HTR1A (0.50) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL24252447 | 0.91 | HTR1A (0.58) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL1584878 | 0.83 | CYP1A2 (0.73) | NPC1NCOA1NCOA3CYP1A2CYP3A4 | |
| SCHEMBL27143212 | 0.80 | CYP1A2 (0.52) | NPC1CYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL24252882 | 0.79 | CYP1A2 (0.55) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL30451870 | 0.79 | CYP1A2 (0.55) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL30880614 | 0.79 | GAK (0.65) | HTR1AADRA1DADRA1AADRA1BGAK | |
| SCHEMBL30380040 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19CYP2D6CLK4 | |
| SCHEMBL25260108 | 0.77 | CYP1A2 (0.52) | NPC1CYP1A2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | HTR1A 2666/4885ADRA1D 3729/4885ADRA1A 4499/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | HTR1A 2666/4885ADRA1D 3729/4885ADRA1A 4499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.