Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451991 | 1.00 | NOTUM (0.38) | NOTUMHTR3ASIRT2PDE4A | |
| SCHEMBL930193 | 0.89 | HTR3A (0.37) | HTR3ASIRT2 | |
| SCHEMBL30783445 | 0.81 | AHR (0.38) | NOTUM | |
| SCHEMBL23505785 | 0.81 | NOTUM (0.49) | NOTUMHTR3APDE4A | |
| SCHEMBL14411960 | 0.78 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL24662927 | 0.78 | GAA (0.37) | NOTUM | |
| SCHEMBL13534195 | 0.78 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL7332352 | 0.78 | NOTUM (0.38) | NOTUMHTR3APDE4A | |
| SCHEMBL24373459 | 0.76 | NOTUM (0.37) | NOTUM | |
| SCHEMBL30774107 | 0.76 | NOTUM (0.37) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | ANNEXON, INC. (US) | 2023-11-14 | — | — | US | disclosed |
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | ANNEXON, INC. | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048930-A1 | INHIBITORS OF COMPLEMENT FACTORS AND USES THEREOF | CFB, CFH, C9 | NOTUM 509/4885HTR3A 3016/4885SIRT2 2428/4885 |
| US-11814404-B2 | Inhibitors of complement factors and uses thereof | CFB, CFH, C9 | NOTUM 509/4885HTR3A 3016/4885SIRT2 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.