SCHEMBL24253263

SCHEMBL24253263

Cc1cc(/C=C2\SC(=S)NC2=O)ccc1/C=C1\SC(=S)NC1=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAT1 P18440 6/20 0.68
MEN1 O00255 3/20 0.66
KMT2A Q03164 3/20 0.66
NPC1 O15118 2/20 0.66
ALDH1A1 P00352 2/20 0.66
POLB P06746 2/20 0.66
GAA P10253 2/20 0.66
MAPT P10636 2/20 0.66
LMNA P02545 1/20 0.66
MYC P01106 3/20 0.62
MAX P61244 3/20 0.62
PDE4B Q07343 1/20 0.61
PDE3A Q14432 1/20 0.61
CSNK2A2 P19784 3/20 0.61
CLK1 P49759 3/20 0.61
CSNK2B P67870 3/20 0.61
CSNK2A1 P68400 3/20 0.61
DYRK1A Q13627 3/20 0.61
DYRK1B Q9Y463 3/20 0.61
PIK3CD O00329 2/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14226382 0.87 NAT1 (0.69) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL17397855 0.84 MYC (0.77) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL17397854 0.84 MYC (0.77) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL17397853 0.84 MYC (0.77) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL8311857 0.82 PDE4B (0.81) MEN1KMT2AALDH1A1POLBMAPT
SCHEMBL8311851 0.82 PDE4B (0.81) MEN1KMT2AALDH1A1POLBMAPT
SCHEMBL14899561 0.82 MYC (0.77) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL20530403 0.81 PTP4A3 (0.71) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL20530402 0.81 PTP4A3 (0.71) NAT1MEN1KMT2ANPC1ALDH1A1
SCHEMBL7557609 0.81 NAT1 (1.00) NAT1MEN1KMT2ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022033993-A1 PHOTOACTIVE MATERIAL CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2022-02-17 WO disclosed