Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTP4A3 | O75365 | 1/20 | 0.71 |
| ▸ | MYC | P01106 | 3/20 | 0.67 |
| ▸ | IL1RN | P18510 | 1/20 | 0.67 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAX | P61244 | 2/20 | 0.60 |
| ▸ | NAT1 | P18440 | 8/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20530402 | 1.00 | PTP4A3 (0.71) | PTP4A3MYCIL1RNERAP1MEN1 | |
| SCHEMBL8178911 | 0.83 | PTP4A3 (1.00) | PTP4A3MYCIL1RNERAP1MEN1 | |
| SCHEMBL8178908 | 0.83 | PTP4A3 (1.00) | PTP4A3MYCIL1RNERAP1MEN1 | |
| SCHEMBL17397853 | 0.83 | MYC (0.77) | PTP4A3MYCMEN1KMT2ANPC1 | |
| SCHEMBL17397854 | 0.83 | MYC (0.77) | PTP4A3MYCMEN1KMT2ANPC1 | |
| SCHEMBL17397855 | 0.83 | MYC (0.77) | PTP4A3MYCMEN1KMT2ANPC1 | |
| SCHEMBL24253263 | 0.81 | NAT1 (0.68) | MYCMEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL6962632 | 0.81 | MYC (1.00) | PTP4A3MYCIL1RNERAP1NPC1 | |
| SCHEMBL6962628 | 0.81 | MYC (1.00) | PTP4A3MYCIL1RNERAP1NPC1 | |
| SCHEMBL12961169 | 0.81 | MYC (1.00) | PTP4A3MYCIL1RNERAP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3192870-B1 | CULTIVATED HEPATOCYTE FOR BLOOD PURIFICATION | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2018-10-17 | — | — | EP | disclosed |