⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19477582 | 0.79 | TRPM8 (0.31) | — | |
| SCHEMBL21276908 | 0.79 | — | — | |
| SCHEMBL20618251 | 0.77 | — | — | |
| SCHEMBL19391252 | 0.77 | — | — | |
| SCHEMBL22905345 | 0.77 | — | — | |
| SCHEMBL16264336 | 0.77 | — | — | |
| SCHEMBL20880791 | 0.77 | — | — | |
| SCHEMBL3232334 | 0.76 | — | — | |
| SCHEMBL19397678 | 0.73 | — | — | |
| SCHEMBL18806384 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048890-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2022-02-17 | — | — | US | disclosed |