Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.39 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.39 |
| ▸ | CHRNG | P07510 | 1/20 | 0.39 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | CHRND | Q07001 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25383534 | 0.79 | ABCB1 (0.39) | ABCB1CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL16441689 | 0.77 | CYP11B2 (0.50) | CYP11B2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30976421 | 0.77 | CYP11B2 (0.50) | CYP11B2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL30826553 | 0.74 | PDE4B (0.44) | MEN1KMT2AKDM4E | |
| SCHEMBL21241613 | 0.74 | PDE4B (0.44) | MEN1KMT2AKDM4E | |
| SCHEMBL17202430 | 0.74 | CYP11B2 (0.48) | CYP11B2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL122002 | 0.73 | CYP11B2 (0.43) | CYP11B2CHRNA1CHRNGCHRNB1CHRNB2 | |
| SCHEMBL31725635 | 0.73 | KDM1A (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL31725748 | 0.73 | MAP3K14 (0.39) | CHRNB2CHRNA4HTT | |
| SCHEMBL12656462 | 0.73 | KDM1A (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |