Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 17/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395911 | 1.00 | HDAC4 (0.48) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19014974 | 0.86 | HDAC6 (0.52) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL30777475 | 0.86 | HDAC6 (0.52) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL22609172 | 0.82 | HDAC4 (0.47) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL24254417 | 0.80 | HDAC6 (0.50) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL19030812 | 0.78 | HDAC4 (0.57) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL18824381 | 0.77 | HDAC4 (0.66) | HDAC4HDAC6HDAC1HDAC8 | |
| SCHEMBL19745563 | 0.76 | HDAC6 (0.51) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL2228278 | 0.76 | HDAC6 (0.53) | HDAC4HDAC6HDAC1HDAC8HDAC5 | |
| SCHEMBL5641740 | 0.76 | HDAC4 (0.57) | HDAC4HDAC6HDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |