Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 2/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17923726 | 0.86 | AR (0.33) | MEN1TTRALBKMT2AAR | |
| SCHEMBL12251119 | 0.82 | MEN1 (0.42) | MEN1TTRALBKMT2AFFAR1 | |
| SCHEMBL28794938 | 0.80 | MEN1 (0.41) | MEN1TTRALBKMT2AFFAR1 | |
| SCHEMBL22898006 | 0.79 | ALDH1A1 (0.38) | ARALDH1A1CYP2A6EGLN2TRPV4 | |
| SCHEMBL29559688 | 0.79 | ALDH1A1 (0.38) | ARALDH1A1CYP2A6EGLN2TRPV4 | |
| SCHEMBL6796667 | 0.79 | MEN1 (0.44) | MEN1TTRALBKMT2AFFAR1 | |
| SCHEMBL22604363 | 0.76 | CYP2A6 (0.37) | MEN1TTRALBKMT2AFFAR1 | |
| SCHEMBL9931297 | 0.76 | MEN1 (0.43) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL29865001 | 0.76 | MEN1 (0.43) | MEN1TTRALBKMT2AHTT | |
| SCHEMBL6796590 | 0.75 | FFAR1 (0.33) | MEN1KMT2AFFAR1ALDH1A1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |