Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 10/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443303 | 0.87 | TRIM24 (0.46) | HSP90AA1TRIM24TRIM33MAPTMEN1 | |
| SCHEMBL4401250 | 0.80 | ERN1 (0.52) | TRIM24TRIM33ERN1CDK1CCR6 | |
| SCHEMBL29954002 | 0.80 | ERN1 (0.52) | TRIM24TRIM33ERN1CDK1CCR6 | |
| SCHEMBL3992952 | 0.75 | HSP90AA1 (0.49) | HSP90AA1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL27814045 | 0.75 | MAPT (0.58) | HSP90AA1TRIM24TRIM33ERN1MAPT | |
| SCHEMBL11825152 | 0.74 | ALDH1A1 (0.59) | MAPTMEN1ALDH1A1KMT2ALMNA | |
| SCHEMBL11537712 | 0.73 | TYR (0.45) | TRIM24TRIM33ERN1MAPTMEN1 | |
| SCHEMBL11543786 | 0.73 | KDM4E (0.41) | TRIM24TRIM33ERN1MAPTMEN1 | |
| SCHEMBL5462848 | 0.72 | ALDH1A1 (0.57) | ERN1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL31268246 | 0.72 | ALDH1A1 (0.57) | ERN1MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035763-A1 | BORON CONTAINING COMPOUNDS AND THEIR USES | 5METIS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |