Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP3 | P08254 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800573 | 0.80 | HTT (0.59) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL10001901 | 0.78 | HTT (0.57) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL25511841 | 0.77 | — | — | |
| SCHEMBL1056413 | 0.76 | HTT (0.55) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL9459556 | 0.76 | HTT (0.55) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL675834 | 0.76 | POLB (0.68) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL5117284 | 0.76 | HTT (0.55) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL17325765 | 0.76 | HTT (0.55) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL6242198 | 0.76 | HTT (0.55) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 | |
| SCHEMBL29098443 | 0.74 | HTT (0.53) | HTTSMN1; SMN2PKMCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035799-A1 | HETEROCYCLE CDK INHIBITORS AND THEIR USE THEREOF | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-02-17 | — | — | WO | disclosed |