SCHEMBL24254917

SCHEMBL24254917

Nc1c(-c2ccccc2)cc(-c2ccccc2)c(N)c1N

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 4/20 0.52
BACE1 P56817 1/20 0.48
SMARCA2 P51531 1/20 0.46
SMARCA4 P51532 1/20 0.46
PBRM1 Q86U86 1/20 0.46
MAOA P21397 1/20 0.44
CYP3A4 P08684 1/20 0.43
TAAR1 Q96RJ0 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MAPT P10636 2/20 0.43
TDO2 P48775 2/20 0.41
LMNA P02545 1/20 0.41
ALOX5 P09917 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
DPP4 P27487 1/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41
IKBKB O14920 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29367789 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
SCHEMBL560129 0.87 ALDH1A1 (0.52) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
SCHEMBL30594444 0.85 HSD17B10 (0.44) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
Water SCHEMBL6229709 0.85 HSD17B10 (0.50) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
SCHEMBL21046679 0.85 HSD17B10 (0.44) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
Hydrochloric Acid SCHEMBL4521255 0.85 HSD17B10 (0.50) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
Hydrogen Sulfide SCHEMBL6229946 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
Methane SCHEMBL22720569 0.85 ALDH1A1 (0.50) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
SCHEMBL5016738 0.83 HSD17B10 (0.52) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4
SCHEMBL4107003 0.82 ALDH1A1 (0.57) ALDH1A1HSD17B10BACE1SMARCA2SMARCA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022034907-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN 東ソー株式会社 2022-02-17 WO disclosed