Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 12/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256015 | 0.92 | ASGR1 (0.53) | ASGR1 | |
| SCHEMBL26879913 | 0.91 | ASGR1 (0.65) | ASGR1 | |
| SCHEMBL24256177 | 0.91 | ASGR1 (0.65) | ASGR1 | |
| SCHEMBL24255997 | 0.89 | ASGR1 (0.50) | ASGR1 | |
| SCHEMBL29384872 | 0.89 | ASGR1 (0.50) | ASGR1 | |
| SCHEMBL30287658 | 0.88 | ASGR1 (0.59) | ASGR1 | |
| SCHEMBL26879907 | 0.86 | ASGR1 (0.57) | ASGR1 | |
| SCHEMBL24256575 | 0.86 | ASGR1 (0.49) | ASGR1 | |
| SCHEMBL24256004 | 0.85 | ASGR1 (0.48) | ASGR1 | |
| SCHEMBL25867253 | 0.81 | ASGR1 (0.57) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |