SCHEMBL24256004

NC(CS)C(=O)NC(COCCC(=O)NCCOCCOCCOCCOC[C@@]12CO[C@@H](O1)[C@@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O)COCCC(=O)NCCOCCOCCOCCOC[C@@]12CO[C@@H](O1)[C@@H](NC(=O)C(F)(F)F)[C@@H](O)[C@H]2O

nearest known ligand 0.48

Predicted protein targets (top 1)

	gene	UniProt	supporting neighbours	confidence
▸	ASGR1	P07306	12/20	0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29384872	0.93	ASGR1 (0.50)	ASGR1
SCHEMBL24255997	0.93	ASGR1 (0.50)	ASGR1
SCHEMBL24256015	0.90	ASGR1 (0.53)	ASGR1
SCHEMBL24256002	0.85	ASGR1 (0.55)	ASGR1
SCHEMBL24256575	0.84	ASGR1 (0.49)	ASGR1
SCHEMBL24725752	0.83	ASGR1 (0.43)	ASGR1
SCHEMBL30287658	0.80	ASGR1 (0.59)	ASGR1
SCHEMBL26879907	0.78	ASGR1 (0.57)	ASGR1
SCHEMBL27180244	0.77	ASGR1 (0.38)	ASGR1
SCHEMBL24256177	0.76	ASGR1 (0.65)	ASGR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2022035997-A1	IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS	AVILAR THERAPEUTICS, INC. (US)	2022-02-17	—	—	WO	disclosed
WO-2022035997-A1	IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS	AVILAR THERAPEUTICS, INC. (US)	2022-02-17	—	—	WO	disclosed