Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286180 | 1.00 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL24256104 | 0.83 | — | — | |
| SCHEMBL22640970 | 0.75 | ASGR1 (0.37) | ASGR1 | |
| SCHEMBL16573636 | 0.69 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL19574104 | 0.69 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL16130851 | 0.69 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL30063145 | 0.68 | — | — | |
| SCHEMBL24724920 | 0.68 | — | — | |
| SCHEMBL21479787 | 0.67 | ASGR1 (0.35) | ASGR1 | |
| SCHEMBL17286213 | 0.67 | ASGR1 (0.35) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022035997-A1 | IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS | AVILAR THERAPEUTICS, INC. (US) | 2022-02-17 | — | — | WO | disclosed |