Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 6/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17286213 | 1.00 | ASGR1 (0.35) | ASGR1MGAMCA1CA2GAA | |
| SCHEMBL24256007 | 0.74 | HCRTR2 (0.44) | ASGR1CA1CA2GAA | |
| SCHEMBL24256485 | 0.74 | HCRTR2 (0.44) | ASGR1CA1CA2GAA | |
| SCHEMBL18722947 | 0.72 | ASGR1 (0.32) | ASGR1 | |
| SCHEMBL18862451 | 0.71 | ASGR1 (0.32) | ASGR1 | |
| SCHEMBL24256219 | 0.71 | — | — | |
| SCHEMBL24256009 | 0.67 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL17286180 | 0.67 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL24256016 | 0.67 | CA2 (0.36) | ASGR1CA1CA2 | |
| SCHEMBL27179385 | 0.66 | ASGR1 (0.36) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199634-A1 | BIFUNCTIONAL SMALL MOLECULES TO TARGET THE SELECTIVE DEGRADATION OF CIRCULATING PROTEINS | YALE UNIVERSITY (US) | 2019-10-17 | — | — | WO | disclosed |