Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24256673 | 0.84 | MTOR (0.59) | USP28USP25 | |
| SCHEMBL22957256 | 0.83 | USP28 (0.85) | USP28USP25 | |
| SCHEMBL22957383 | 0.82 | USP28 (1.00) | USP28USP25 | |
| SCHEMBL22957479 | 0.81 | USP28 (1.00) | USP28USP25 | |
| SCHEMBL22957254 | 0.81 | USP25 (1.00) | USP28USP25 | |
| SCHEMBL22957376 | 0.79 | USP28 (1.00) | USP28USP25 | |
| SCHEMBL22957316 | 0.79 | USP25 (1.00) | USP28USP25 | |
| SCHEMBL22957278 | 0.78 | USP25 (1.00) | USP28USP25 | |
| SCHEMBL22957398 | 0.78 | USP28 (1.00) | USP28USP25 | |
| SCHEMBL22957508 | 0.77 | USP25 (1.00) | USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022035806-A1 | FUSED TRICYCLIC PYRIMIDINE-THIENO-PYRIDINE SMALL MOLECULE INHIBITORS OF UBIQUITIN-SPECIFIC PROTEASE 28 | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2022-02-17 | — | — | WO | disclosed |