Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12230602 | 0.93 | NPSR1 (0.53) | RAB9ASMN1; SMN2NPC1HPGDNPSR1 | |
| SCHEMBL2428264 | 0.88 | NPC1 (0.61) | RAB9ASMN1; SMN2NPC1HPGDNPSR1 | |
| Formaldehyde SCHEMBL27861058 | 0.71 | NPC1 (0.87) | RAB9ASMN1; SMN2NPC1HPGDNPSR1 | |
| SCHEMBL28244373 | 0.66 | HPGD (0.56) | RAB9ASMN1; SMN2NPC1HPGDNPSR1 | |
| SCHEMBL27914985 | 0.65 | IDH1 (0.42) | RAB9ASMN1; SMN2ALDH1A1TDP1PARP11 | |
| SCHEMBL28019337 | 0.65 | NPC1 (0.73) | RAB9ASMN1; SMN2NPC1HPGDNPSR1 | |
| SCHEMBL28317914 | 0.65 | CYP2D6 (0.38) | RAB9ASMN1; SMN2NPC1HPGDMEN1 | |
| 4,4'-Methylenedianiline SCHEMBL28946261 | 0.64 | CYP3A4 (0.78) | RAB9ASMN1; SMN2NPC1CYP3A4ALDH1A1 | |
| SCHEMBL8771463 | 0.64 | CYP3A4 (0.78) | RAB9ASMN1; SMN2NPC1CYP3A4ALDH1A1 | |
| SCHEMBL202238 | 0.64 | CYP3A4 (0.78) | RAB9ASMN1; SMN2NPC1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853443-B2 | Process for preparing an isocyanate | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8853443-B2 | Process for preparing an isocyanate | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| US-8853443-B2 | Process for preparing an isocyanate | BASF SE (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2367783-B1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| EP-2367783-B1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2013-01-09 | — | — | EP | disclosed |
| CN-102282127-A | method for producing isocyanates | — | 2011-12-14 | — | — | CN | disclosed |
| US-20110263892-A1 | PROCESS FOR PREPARING AN ISOCYANATE | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110263892-A1 | PROCESS FOR PREPARING AN ISOCYANATE | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| US-20110263892-A1 | PROCESS FOR PREPARING AN ISOCYANATE | BASF SE (DE) | 2011-10-27 | — | — | US | disclosed |
| EP-2367783-A1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010057909-A1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010057909-A1 | METHOD FOR PRODUCING AN ISOCYANATE | BASF SE (DE) | 2010-05-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263892-A1 | PROCESS FOR PREPARING AN ISOCYANATE | IDH1, IDH2, GMNN | RAB9A 2291/4885SMN1; SMN2 2982/4885NPC1 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.