Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 12/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 11/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 11/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 11/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 11/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 11/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 11/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 11/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31682110 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL31682005 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22080335 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL31682058 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22080464 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL24257951 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22080239 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22080339 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL22079923 | 1.00 | HDAC1 (0.46) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL31682114 | 0.97 | HDAC1 (0.43) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | SANOFI (FR) | 2022-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220048968-A1 | INSULIN CONJUGATES | IAPP, INSR, IGF1R | HDAC1 2572/4885HDAC3 3410/4885HDAC4 3246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.