Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24258297 | 0.78 | SLC6A4 (0.35) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22944895 | 0.76 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL23891941 | 0.74 | USP2 (0.43) | — | |
| SCHEMBL19779413 | 0.74 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL25819859 | 0.73 | SLC6A4 (0.36) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22944898 | 0.73 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL16377420 | 0.71 | SLC6A4 (0.35) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL24920411 | 0.71 | SLC6A4 (0.38) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL23086597 | 0.70 | SLC6A4 (0.37) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7939755 | 0.70 | SLC6A4 (0.35) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177612-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2022-02-23 | — | — | EP | disclosed |