Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17779794 | 0.83 | — | — | |
| SCHEMBL1353040 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL11163492 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL1353039 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1 | |
| SCHEMBL20438201 | 0.74 | MGAM (0.48) | ALDH1A1TDP1LMNA | |
| SCHEMBL19872127 | 0.74 | GRIK1 (0.36) | LMNAALOX15BLMPMP22 | |
| SCHEMBL22171386 | 0.74 | — | — | |
| SCHEMBL22756796 | 0.74 | — | — | |
| SCHEMBL19013515 | 0.74 | — | — | |
| SCHEMBL23939979 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177612-B1 | OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES | NUEVOLUTION AS (DK) | 2022-02-23 | — | — | EP | disclosed |