SCHEMBL24258569

SCHEMBL24258569

C=C1OP(=O)(S)OC[C@H]2O[C@@H](n3cnc4c(=O)n5cc[nH]c5nc43)C[C@@H]2OP(=O)(S)OC[C@H]2C[C@@H](n3cnc4c(N)ncnc43)[C@H]12

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21263931 0.90 STING1 (0.50) STING1
SCHEMBL24681181 0.83 STING1 (0.46) STING1
SCHEMBL21263873 0.81 STING1 (0.52) STING1
SCHEMBL24258629 0.81 STING1 (0.47) STING1
SCHEMBL24321945 0.80 STING1 (0.59) STING1
SCHEMBL24258544 0.79 STING1 (0.46) STING1
SCHEMBL24258595 0.79 STING1 (0.46) STING1
SCHEMBL24258617 0.79 STING1 (0.46) STING1
SCHEMBL24444136 0.79 STING1 (0.55) STING1
SCHEMBL21263932 0.79 STING1 (0.58) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752516-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-02-23 — — EP disclosed
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