SCHEMBL24258629

SCHEMBL24258629

C=C1OP(=O)(S)OC[C@H]2O[C@@H](n3cnc4c(N)ncnc43)C[C@@H]2OP(=O)(S)OC[C@H]2C[C@@H](n3cnc4c(=O)n5nnnc5[nH]c43)[C@H]12

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21263937 0.90 STING1 (0.49) STING1
SCHEMBL24258569 0.81 STING1 (0.47) STING1
SCHEMBL24681181 0.80 STING1 (0.46) STING1
SCHEMBL24258617 0.80 STING1 (0.46) STING1
SCHEMBL24258595 0.80 STING1 (0.46) STING1
SCHEMBL24258544 0.80 STING1 (0.46) STING1
SCHEMBL24258590 0.79 STING1 (0.50) STING1
SCHEMBL24258576 0.79 STING1 (0.50) STING1
SCHEMBL24258533 0.79 STING1 (0.50) STING1
SCHEMBL24258588 0.79 STING1 (0.50) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752516-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-02-23 — — EP disclosed
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