SCHEMBL24258641

SCHEMBL24258641

Nc1ncnc2c1ncn2[C@@H]1CC2COP(=O)(S)O[C@@H]3[C@H](F)[C@@H](COP(=O)(S)OC[C@H]21)O[C@H]3n1cnc2c1ncn1ccnc21

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21263867 1.00 STING1 (0.59) STING1
SCHEMBL21263842 0.94 STING1 (0.62) STING1
SCHEMBL21263826 0.94 STING1 (0.62) STING1
SCHEMBL21263918 0.90 STING1 (0.51) STING1
SCHEMBL21263812 0.90 STING1 (0.51) STING1
SCHEMBL21263934 0.89 STING1 (0.49) STING1
SCHEMBL21263824 0.86 STING1 (0.53) STING1
SCHEMBL24258637 0.86 STING1 (0.55) STING1
SCHEMBL24258657 0.86 STING1 (0.55) STING1
SCHEMBL24258643 0.86 STING1 (0.55) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752516-B1 CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS BRISTOL MYERS SQUIBB CO (US) 2022-02-23 — — EP disclosed
Send feedback