Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 6/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | MAX | P61244 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL11402189 | 0.98 | ADORA2A (0.56) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| Methane SCHEMBL5243858 | 0.96 | ADORA2A (0.55) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| Ethane SCHEMBL8441819 | 0.96 | ADORA2A (0.55) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL28019418 | 0.82 | NT5E (0.56) | ADORA2AADORA1LMNAPOLBNT5E | |
| SCHEMBL3618520 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL31265529 | 0.80 | ADORA2A (0.56) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL693661 | 0.79 | NT5E (0.62) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL3300391 | 0.79 | BACE1 (0.66) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL28311336 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1TLR7ADRB2MAPK1 | |
| SCHEMBL10643394 | 0.79 | L3MBTL1 (0.63) | ADORA2AADORA1TLR7ADRB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136851-A | Preparation method and application of quinoline ester compound | 楚雄师范学院 | 2025-06-13 | — | — | CN | claimed |
| CN-117397690-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preventing and controlling agricultural bacteria | 兰州大学 | 2024-01-16 | — | — | CN | claimed |
| CN-116991036-A | Fluorine-silicon modified polyurethane photoresist and preparation method thereof | 常州大学 | 2023-11-03 | — | — | CN | claimed |
| CN-115197134-A | Preparation method and application of camphorsulfonate compounds | 南京林业大学 | 2022-10-18 | — | — | CN | claimed |
| CN-112608275-A | Application of 2, 8-bis (trifluoromethyl) -4-hydroxyquinoline derivative in preparation and prevention and treatment of agricultural diseases | 兰州大学 | 2021-04-06 | — | — | CN | claimed |
| EP-2205083-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | Merck Sharp & Dohme Corp. (US) | 2010-07-14 | — | — | EP | claimed |
| WO-2009045382-A1 | SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS | MERCK & CO., INC. (US) | 2009-04-09 | — | — | WO | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-12459921-B2 | Isoindoline compound, preparation method, pharmaceutical composition and use thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-04 | — | — | US | disclosed |
| CN-120136851-A | Preparation method and application of quinoline ester compound | 楚雄师范学院 | 2025-06-13 | — | — | CN | disclosed |
| EP-4055014-B1 | PYRROLIDINE AND PIPERIDINE COMPOUNDS | YUHAN CORP (KR) | 2025-04-30 | — | — | EP | disclosed |
| CN-119139301-A | Application of 2, 8-trifluoromethyl quinoline derivative in preventing and treating cow mastitis pathogenic bacteria | 兰州大学 | 2024-12-17 | — | — | CN | disclosed |
| CN-115197134-B | Preparation method and application of camphorsulfonate compounds | 南京林业大学 | 2024-07-30 | — | — | CN | disclosed |
| EP-0055061-A1 | Male gametocide method in small grain plants | UNION CARBIDE CORPORATION (US) | 1982-06-30 | — | — | EP | disclosed |
| EP-0049555-A1 | 2-Trifluoromethyl-4-hydroxy-3 quinoline-carboxylic-acid derivatives and their preparation | ROUSSEL-UCLAF (FR) | 1982-04-14 | — | — | EP | disclosed |
| EP-0049555-A1 | 2-Trifluoromethyl-4-hydroxy-3 quinoline-carboxylic-acid derivatives and their preparation | ROUSSEL-UCLAF (FR) | 1982-04-14 | — | — | EP | disclosed |
| US-4267333-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE AGRICULTURAL PRODUCTS COMPANY, INC. (US) | 1981-05-12 | — | — | US | disclosed |
| US-4251661-A | Preparation of 2-trifluoromethyl cinchoninic acids | UNION CARBIDE CORPORATION (US) | 1981-02-17 | — | — | US | disclosed |
| EP-0012639-A2 | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459921-B2 | Isoindoline compound, preparation method, pharmaceutical composition and use thereof | CUL4B, CUL4A, UBQLN1 | ADORA2A 3261/4885ADORA1 3126/4885TLR7 2332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.