Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 11/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.45 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.45 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11114536 | 0.87 | DPP7 (0.49) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL11114906 | 0.84 | DPP7 (0.59) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL19401566 | 0.84 | TLR2 (0.48) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL11112359 | 0.82 | DPP7 (0.39) | TLR2DPP7RRM1GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL11110122 | 0.82 | DPP7 (0.57) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL11109536 | 0.82 | DPP7 (0.67) | TLR2DPP7RRM1GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL11111559 | 0.81 | DPP7 (0.38) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL11111978 | 0.81 | DPP7 (0.65) | TLR2DPP7RRM1GNAI3GNAO1 | |
| Hydrochloric Acid SCHEMBL11122478 | 0.80 | DPP7 (0.63) | TLR2DPP7RRM1GNAI3GNAO1 | |
| SCHEMBL24256577 | 0.77 | DPP7 (0.37) | TLR2DPP7RRM1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-B1 | PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma AG (DE) | 2022-02-23 | — | — | EP | disclosed |