SCHEMBL24256577

SCHEMBL24256577

CCSC[C@H](N)C(=O)NCCC(=O)NCCC(=O)NCCC(C)=O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 2/20 0.37
TLR2 O60603 14/20 0.36
RRM1 P23921 1/20 0.35
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25083937 0.90 TLR2 (0.33) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL26700213 0.86 FNTA (0.38) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL26700211 0.86 FNTA (0.38) DPP7RRM1GNAI3GNAO1GNAI1
SCHEMBL24256576 0.82 TERT (0.36) DPP7TLR2RRM1
SCHEMBL18738637 0.79 TLR2 (0.50) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL11114536 0.79 DPP7 (0.49) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL24259720 0.77 TLR2 (0.49) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL11114906 0.76 DPP7 (0.59) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL24932780 0.75 DPP7 (0.35) DPP7TLR2RRM1GNAI3GNAO1
SCHEMBL24256290 0.75 TSHR (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022035997-A1 IN VIVO ASSEMBLY OF ASGPR BINDING THERAPEUTICS AVILAR THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed