Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18818920 | 0.78 | TDP1 (0.45) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL14667663 | 0.77 | SMN1; SMN2 (0.55) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL2103664 | 0.73 | — | — | |
| SCHEMBL133541 | 0.73 | — | — | |
| SCHEMBL11582606 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL637801 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL637786 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL1546190 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL11410952 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 | |
| SCHEMBL7899825 | 0.70 | FOLH1 (0.52) | SLC22A6LMNATDP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3432934-B1 | PRODRUGS OF CYTOTOXIC AGENTS WITH ENZYMATICALLY CLEAVABLE GROUPS | Bayer Pharma AG (DE) | 2022-02-23 | — | — | EP | disclosed |