Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754460 | 1.00 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL29754610 | 0.92 | TYK2 (0.79) | TYK2 | |
| SCHEMBL24263470 | 0.92 | TYK2 (0.79) | TYK2 | |
| SCHEMBL24263407 | 0.92 | TYK2 (0.79) | TYK2 | |
| SCHEMBL24263416 | 0.91 | TYK2 (0.84) | TYK2 | |
| SCHEMBL24263281 | 0.90 | TYK2 (0.82) | TYK2 | |
| SCHEMBL31218852 | 0.89 | TYK2 (0.62) | TYK2PDE4D | |
| SCHEMBL24263475 | 0.87 | TYK2 (0.73) | TYK2 | |
| SCHEMBL22229005 | 0.86 | TYK2 (1.00) | TYK2 | |
| SCHEMBL31218938 | 0.86 | TYK2 (0.60) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |