Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263296 | 0.86 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL29754460 | 0.86 | TYK2 (0.78) | TYK2PDE4D | |
| SCHEMBL26101149 | 0.85 | TYK2 (0.82) | TYK2 | |
| SCHEMBL24263493 | 0.83 | TYK2 (0.77) | TYK2PDE4D | |
| SCHEMBL22252601 | 0.79 | TYK2 (0.77) | TYK2PDE4D | |
| SCHEMBL24263470 | 0.78 | TYK2 (0.79) | TYK2 | |
| SCHEMBL24263407 | 0.78 | TYK2 (0.79) | TYK2 | |
| SCHEMBL29754610 | 0.78 | TYK2 (0.79) | TYK2 | |
| SCHEMBL31218807 | 0.77 | TYK2 (0.74) | TYK2PDE4D | |
| SCHEMBL31218652 | 0.77 | TYK2 (0.54) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |