Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24263534 | 0.89 | TYK2 (0.54) | TYK2JAK1 | |
| SCHEMBL24263286 | 0.88 | TYK2 (0.55) | TYK2JAK1 | |
| SCHEMBL31245725 | 0.88 | TYK2 (0.55) | TYK2JAK1 | |
| SCHEMBL24263518 | 0.88 | TYK2 (0.55) | TYK2JAK1 | |
| SCHEMBL24263278 | 0.88 | TYK2 (0.56) | TYK2STAT3 | |
| SCHEMBL24263421 | 0.87 | TYK2 (0.55) | TYK2STAT3 | |
| SCHEMBL24263289 | 0.86 | TYK2 (0.54) | TYK2STAT3 | |
| SCHEMBL18161079 | 0.86 | TYK2 (0.69) | TYK2JAK1 | |
| SCHEMBL24263282 | 0.85 | TYK2 (0.52) | TYK2JAK1 | |
| SCHEMBL31245741 | 0.85 | TYK2 (0.52) | TYK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |