Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.54 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31245725 | 0.93 | TYK2 (0.55) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL24263286 | 0.93 | TYK2 (0.55) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL24263518 | 0.93 | TYK2 (0.55) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL24263282 | 0.91 | TYK2 (0.52) | TYK2JAK1 | |
| SCHEMBL31245741 | 0.91 | TYK2 (0.52) | TYK2JAK1 | |
| SCHEMBL24263430 | 0.89 | TYK2 (0.52) | TYK2JAK1 | |
| SCHEMBL31245698 | 0.89 | TYK2 (0.53) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL22252452 | 0.87 | TYK2 (0.58) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL18161079 | 0.87 | TYK2 (0.69) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL22273050 | 0.86 | TYK2 (0.58) | TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022037694-A1 | A CLASS OF FIVE- AND SIX-MEMBERED HETEROCYCLIC COMPOUNDS AND USE THEREOF AS PROTEIN RECEPTOR KINASE INHIBITORS | 轶诺(浙江)药业有限公司 | 2022-02-24 | — | — | WO | disclosed |