Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.51 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALB | P02768 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL9012912 | 0.97 | NR1I2 (0.52) | NR1I2PGRPPARGESR1TDP1 | |
| Trifluoroacetic Acid SCHEMBL9012917 | 0.97 | NR1I2 (0.52) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL5493394 | 0.93 | NR1I2 (0.49) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL4205225 | 0.93 | NR1I2 (0.49) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL17897732 | 0.93 | NR1I2 (0.55) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL16156786 | 0.93 | NR1I2 (0.55) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL15100214 | 0.93 | NR1I2 (0.55) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL14409663 | 0.93 | NR1I2 (0.55) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL14885179 | 0.93 | NR1I2 (0.55) | NR1I2PGRPPARGESR1TDP1 | |
| SCHEMBL9781665 | 0.92 | NR1I2 (0.54) | NR1I2PGRPPARGESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11542279-B2 | Solid forms of ceftolozane and processes for preparing | MERCK SHARP & DOHME LLC (US) | 2023-01-03 | — | — | US | disclosed |
| US-20220056045-A1 | SOLID FORMS OF CEFTOLOZANE AND PROCESSES FOR PREPARING | MERCK SHARP & DOHME CORP. (US) | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542279-B2 | Solid forms of ceftolozane and processes for preparing | PPP1CC, CCNC, AMPD3 | NR1I2 3016/4885PGR 4876/4885PPARG 3202/4885 |
| US-20220056045-A1 | SOLID FORMS OF CEFTOLOZANE AND PROCESSES FOR PREPARING | PPP1CC, CCNC, AMPD3 | NR1I2 3016/4885PGR 4876/4885PPARG 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.