Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205225 | 1.00 | NR1I2 (0.49) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL17529038 | 0.93 | NR1I2 (0.49) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL24263657 | 0.93 | NR1I2 (0.54) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL19407782 | 0.93 | NR1I2 (0.45) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL6385493 | 0.93 | NR1I2 (0.49) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL10856495 | 0.91 | NR1I2 (0.59) | NR1I2HTR2CPGRPPARGESR1 | |
| Trifluoroacetic Acid SCHEMBL9012917 | 0.91 | NR1I2 (0.52) | NR1I2HTR2CPGRPPARGESR1 | |
| Trifluoroacetic Acid SCHEMBL9012912 | 0.91 | NR1I2 (0.52) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL18939191 | 0.89 | NR1I2 (0.43) | NR1I2HTR2CPGRPPARGESR1 | |
| SCHEMBL18939193 | 0.89 | NR1I2 (0.43) | NR1I2HTR2CPGRPPARGESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556389-B9 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-09-09 | — | — | EP | disclosed |
| EP-1556389-B3 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2015-04-01 | — | — | EP | disclosed |
| EP-1556389-B1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC (JP) | 2007-07-25 | — | — | EP | disclosed |
| US-20070037786-A1 | Cephem compounds | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2007-02-15 | — | — | US | disclosed |
| US-7129232-B2 | For therapy of of infectious diseases | ASTELLAS PHARMA INC. (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20040132994-A1 | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037786-A1 | Cephem compounds | CEP170, ABCB11, SLC7A1 | NR1I2 603/4885HTR2C 855/4885PGR 2604/4885 |
| US-20040132994-A1 | Cephem compounds | CEP170, ABCB11, RCC2 | NR1I2 385/4885HTR2C 674/4885PGR 3749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.