Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24633632 | 0.88 | DAO (0.47) | DAONPC1RAB9AHTR2AHTR2C | |
| SCHEMBL7730038 | 0.86 | DAO (0.37) | DAONPC1HPGDMAPK1HTT | |
| SCHEMBL13002543 | 0.84 | RARB (0.51) | HTR2AGPR84RARBRARARARG | |
| SCHEMBL13002697 | 0.84 | RARB (0.51) | HTR2AGPR84RARBRARARARG | |
| SCHEMBL13002280 | 0.82 | RARB (0.44) | DAOSKP2RARBRARARARG | |
| SCHEMBL13636530 | 0.82 | PTGS2 (0.38) | DAOPTGS2CYP3A4HTR2AHTR2C | |
| SCHEMBL7734949 | 0.81 | PTGS2 (0.37) | DAOPTGS2CYP3A4HTR2AGPR84 | |
| SCHEMBL13002921 | 0.81 | RARB (0.43) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL15317532 | 0.81 | PTGS2 (0.37) | DAOPTGS2CYP3A4HTR2AGPR84 | |
| SCHEMBL7735067 | 0.81 | DAO (0.36) | DAOHTR2AGPR84FAAHRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022040607-A1 | SMALL MOLECULE ALBUMIN BINDERS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2022-02-24 | — | — | WO | disclosed |