Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 4/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | KHK | P50053 | 2/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266549 | 0.89 | HTR6 (0.41) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL24265686 | 0.87 | KDM1A (0.44) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL29574126 | 0.87 | KDM1A (0.44) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL24265925 | 0.86 | INPPL1 (0.40) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL29574548 | 0.86 | INPPL1 (0.40) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL24265824 | 0.86 | HTR6 (0.44) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL24266542 | 0.85 | HTR6 (0.41) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL29573778 | 0.85 | HTR6 (0.46) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL24265507 | 0.85 | HTR6 (0.46) | MAP4K3KCNH2GPR119HTR6KDM1A | |
| SCHEMBL29574663 | 0.85 | HTR6 (0.41) | MAP4K3KCNH2GPR119HTR6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230322744-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| US-20230322744-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. | 2023-10-12 | — | — | US | disclosed |
| CN-116507326-A | Compounds as GLP-1R agonists | 拓臻制药公司 | 2023-07-28 | — | — | CN | disclosed |
| EP-4199919-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
| WO-2022040600-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2022-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230322744-A1 | COMPOUNDS AS GLP-1R AGONISTS | GLP1R, GIPR, GCGR | MAP4K3 1285/4885KCNH2 3089/4885GPR119 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.