Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 8/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.40 |
| ▸ | PPARD | Q03181 | 7/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2426032 | 0.86 | EPHX2 (0.42) | RXRARXRBRXRGPPARGEPHX2 | |
| SCHEMBL11010315 | 0.84 | LDHA (0.66) | LDHAPKMALOX15 | |
| SCHEMBL2424748 | 0.84 | IDO1 (0.45) | PPARAPPARGEPHX2PTGDR2 | |
| SCHEMBL2048973 | 0.84 | LDHA (0.54) | LDHAPKMALOX15 | |
| SCHEMBL28672180 | 0.83 | LDHA (0.52) | LDHAPKMALOX15 | |
| SCHEMBL28670825 | 0.81 | LDHA (0.50) | LDHAPKMALOX15 | |
| SCHEMBL3773692 | 0.81 | LDHA (0.50) | LDHAPKMALOX15 | |
| SCHEMBL31361313 | 0.81 | LDHA (0.50) | LDHAPKMALOX15 | |
| SCHEMBL15246756 | 0.78 | PPARG (0.54) | PPARAPPARGEPHX2 | |
| SCHEMBL491026 | 0.77 | LDHA (0.71) | LDHAPKMALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011114148-A1 | 4H- [1, 2, 4] TRIAZOLO [5, 1 -B] PYRIMIDIN-7 -ONE DERIVATIVES AS CCR2B RECEPTOR ANTAGONISTS | ASTRAZENECA AB (SE) | 2011-09-22 | — | — | WO | disclosed |