Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267085 | 0.84 | AR (0.38) | CHEK1PDGFRBPDGFRA | |
| SCHEMBL22565333 | 0.84 | AR (0.32) | — | |
| SCHEMBL24267288 | 0.82 | SLC22A12 (0.35) | CHEK1 | |
| SCHEMBL24267289 | 0.79 | AR (0.41) | CHEK1 | |
| SCHEMBL1846308 | 0.77 | HPGDS (0.39) | — | |
| SCHEMBL22165375 | 0.76 | CYP11B1 (0.40) | — | |
| SCHEMBL29919284 | 0.73 | HPGDS (0.36) | — | |
| SCHEMBL12806805 | 0.73 | KDM4E (0.42) | — | |
| SCHEMBL1675480 | 0.68 | MAOB (0.51) | PDGFRBPDGFRA | |
| SCHEMBL24379103 | 0.67 | AR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |