Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17630319 | 0.90 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL21245661 | 0.89 | ALDH1A1 (0.61) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL1640562 | 0.88 | ALDH1A1 (0.60) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL210786 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL29723200 | 0.87 | ALDH1A1 (0.69) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL26655535 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL22471238 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL30306129 | 0.85 | ALDH1A1 (0.57) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL5240348 | 0.83 | ALDH1A1 (0.64) | ALDH1A1KMT2ALMNAMAPTTHRB | |
| SCHEMBL10128069 | 0.83 | ALDH1A1 (0.59) | ALDH1A1KMT2ALMNAMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2023-03-02 | — | — | US | disclosed |
| US-20230048132-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2023-02-16 | — | — | US | disclosed |
| US-20220220103-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2022-07-14 | — | — | US | disclosed |
| US-20220056037-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | SPV THERAPEUTICS INC. | 2022-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056037-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | ALDH1A1 4227/4885KMT2A 962/4885LMNA 1299/4885 |
| US-20230065740-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | ALDH1A1 4227/4885KMT2A 962/4885LMNA 1299/4885 |
| US-20220220103-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | ALDH1A1 4227/4885KMT2A 962/4885LMNA 1299/4885 |
| US-20230048132-A1 | CYCLIN-DEPENDENT KINASE INHIBITORS | CDK2, CDK1, CCNK | ALDH1A1 4227/4885KMT2A 962/4885LMNA 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.