Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | TGM1 | P22735 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898643 | 0.80 | CHRM2 (0.46) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL4898628 | 0.80 | CHRM2 (0.46) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL4891480 | 0.80 | CHRM2 (0.46) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL4891486 | 0.80 | CHRM2 (0.46) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL26046497 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL1711301 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL6097554 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL1711248 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL1711809 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 | |
| SCHEMBL12275013 | 0.76 | CHRM2 (0.42) | HSD11B1CHRM2CHRM1CHRM3NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |