Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 4/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24267492 | 0.87 | PGR (0.47) | PGRARHRH3MPOMRGPRX4 | |
| SCHEMBL16483388 | 0.86 | AR (0.48) | PGRARHRH3MRGPRX4ACACB | |
| SCHEMBL24267088 | 0.85 | PGR (0.46) | PGRARHRH3MPOMRGPRX4 | |
| SCHEMBL14553122 | 0.85 | AR (0.47) | PGRARHRH3MRGPRX4ACACB | |
| SCHEMBL31498678 | 0.83 | AR (0.50) | PGRARHRH3 | |
| SCHEMBL22565823 | 0.82 | PGR (0.62) | PGRARBCL2A1 | |
| SCHEMBL22557803 | 0.82 | PGR (0.43) | PGRARHRH3MPOBCL2A1 | |
| SCHEMBL20046664 | 0.82 | PGR (0.62) | PGRARBCL2A1 | |
| SCHEMBL22557802 | 0.82 | PGR (0.43) | PGRARHRH3MPOBCL2A1 | |
| SCHEMBL15575031 | 0.82 | PGR (0.62) | PGRARBCL2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3957633-A1 | A CLASS OF BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUNDS FOR TARGETED DEGRADATION OF ANDROGEN RECEPTORS AND USE THEREOF | Hinova Pharmaceuticals Inc. (CN) | 2022-02-23 | — | — | EP | disclosed |