Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22032824 | 0.77 | TP53 (0.44) | — | |
| SCHEMBL13280688 | 0.77 | — | — | |
| SCHEMBL15709700 | 0.77 | — | — | |
| SCHEMBL22306040 | 0.71 | BACE1 (0.47) | CTSDBACE1 | |
| SCHEMBL19110540 | 0.69 | TAAR1 (0.43) | — | |
| SCHEMBL9107623 | 0.69 | ALDH1A1 (0.52) | — | |
| SCHEMBL17635526 | 0.68 | — | — | |
| SCHEMBL22081739 | 0.68 | CYP3A4 (0.48) | — | |
| SCHEMBL26068801 | 0.68 | — | — | |
| SCHEMBL10154490 | 0.67 | BACE1 (0.58) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022068848-A1 | 3-[(1H-PYRAZOL-4-YL)OXY]PYRAZIN-2-AMINE COMPOUNDS AS HPK1 INHIBITOR AND USE THEREOF | BEIGENE, LTD. (KY) | 2022-04-07 | — | — | WO | disclosed |