Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NQO1 | P15559 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335959 | 0.80 | MTNR1A (0.54) | MAPTPLK1PARP10RAB9ANPC1 | |
| SCHEMBL24196870 | 0.73 | NQO1 (0.67) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL18894356 | 0.73 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL23280 | 0.73 | KMT2A (1.00) | KMT2AMEN1LMNACYP1A2TDP1 | |
| SCHEMBL28037693 | 0.72 | TEAD1 (0.43) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| Phenacetin SCHEMBL28388594 | 0.71 | KMT2A (0.96) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL28630552 | 0.71 | KMT2A (0.96) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL28570302 | 0.71 | KMT2A (0.96) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL10630698 | 0.71 | KMT2A (0.96) | KMT2AMEN1LMNACYP1A2TDP1 | |
| Phenacetin SCHEMBL28498098 | 0.71 | KMT2A (0.96) | KMT2AMEN1LMNACYP1A2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056447-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |