Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPGM | P07738 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | EIF4E | P06730 | 9/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24272059 | 0.94 | BPGM (0.54) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24271879 | 0.93 | BPGM (0.66) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24272105 | 0.92 | BPGM (0.51) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24272051 | 0.92 | BPGM (0.51) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24272002 | 0.92 | BPGM (0.51) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24271860 | 0.92 | BPGM (0.51) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24271805 | 0.91 | BPGM (0.51) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24272103 | 0.91 | BPGM (0.57) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL24272046 | 0.91 | BPGM (0.55) | BPGMMEN1KMT2AGAAXDH | |
| SCHEMBL26750614 | 0.90 | BPGM (0.56) | BPGMMEN1KMT2AGAAXDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022056447-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |