SCHEMBL2427362

SCHEMBL2427362

CCC1=C(CC)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CC)c5CC)C(CC)=C4CC)c(CC)c3CC.[Pd]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ HSD17B10 Q99714 3/20 0.33
▸ MEN1 O00255 2/20 0.33
▸ MAPT P10636 2/20 0.33
▸ THRB P10828 2/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ KMT2A Q03164 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ USP2 O75604 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ HSPD1 P10809 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ HPGD P15428 1/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ NFKB1 P19838 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33
▸ RECQL P46063 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29410673 0.98 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL37749 0.98 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL20293861 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL31252898 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL30909508 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL2333822 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL75881 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL11018080 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL1436136 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1
SCHEMBL3454319 0.96 HSD17B10 (0.33) HSD17B10MEN1MAPTTHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4569015-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS Promega Corporation (US) 2025-06-18 — — EP claimed
US-12186076-B2 Optical based glucose sensor MEDTRONIC, INC. (US) 2025-01-07 — — US claimed
WO-2024191851-A2 OXYGEN CONSUMPTION ASSAY PROMEGA CORPORATION (US) 2024-09-19 — — WO claimed
US-20240302339-A1 OXYGEN CONSUMPTION ASSAY PROMEGA CORP (US) 2024-09-12 — — US claimed
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION 2024-02-22 — — US claimed
WO-2024036277-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS PROMEGA CORPORATION (US) 2024-02-15 — — WO claimed
CN-115110308-B External heat and internal cold Janus antibacterial material with light responsiveness and preparation method thereof 南通大学 2024-01-30 — — CN claimed
EP-4291090-A1 OPTICAL BASED GLUCOSE SENSOR Medtronic, Inc. (US) 2023-12-20 — — EP claimed
WO-2023091915-A1 CHEMICAL TRANSDUCTION SYSTEM IN AN OPTICAL ENZYMATIC ANALYTE PHYSIOLOGICAL SENSOR METRONOM HEALTH, INC. (US) 2023-05-25 — — WO claimed
US-11629203-B2 Photopolymerisable composition, material obtained by polymerising such a composition and 3D printing method using such a composition ECOLE NORMALE SUPERIEURE DE LYON (FR) 2023-04-18 — — US claimed
CN-115110308-A External-heating internal-cooling Janus antibacterial material with light responsiveness and preparation method thereof 南通大学 2022-09-27 — — CN claimed
WO-2022173643-A1 OPTICAL BASED GLUCOSE SENSOR MEDTRONIC, INC. (US) 2022-08-18 — — WO claimed
US-20220248986-A1 OPTICAL BASED GLUCOSE SENSOR MEDTRONIC, INC. 2022-08-11 — — US claimed
EP-4748893-A1 PHOTOCURABLE RESIN COMPOSITION, ADHESIVE, SEALING MATERIAL, COATING AGENT, CURED PRODUCT, SEMICONDUCTOR DEVICE, ELECTRONIC COMPONENT, AND CURING, BONDING, SEALING, AND COATING METHODS USING PHOTOCURABLE RESIN COMPOSITION Namics Corporation (JP) 2026-05-27 — — EP disclosed
US-20260000322-A1 DETECTION OF CHANGES IN PATIENT HEALTH BASED ON GLUCOSE DATA MEDTRONIC INC (US) 2026-01-01 — — US disclosed
US-12426811-B2 Detection of changes in patient health based on glucose data MEDTRONIC, INC. (US) 2025-09-30 — — US disclosed
US-8917018-B2 Nanomatrix separation of chromophores and uses thereof in luminescent devices RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-12-23 — — US disclosed
US-8503073-B2 Light coupling device and system, and method for manufacturing the device and system CSEM Centre Suisse d'Electronique et de Microtechnique S.A.—Recherche et Developpement (CH) 2013-08-06 — — US disclosed
US-20110215716-A1 NANOMATRIX SEPARATION OF CHROMOPHORES AND USES THEREOF IN LUMINESCENT DEVICES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2011-09-08 — — US disclosed
US-20090316429-A1 LIGHT COUPLING DEVICE AND SYSTEM, AND METHOD FOR MANUFACTURING THE DEVICE AND SYSTEM CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPMENT (CH) 2009-12-24 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059961-A1 BIOCOMPATIBLE OXYGEN-SENSITIVE MATERIALS COXFA4L2, LOXL1, LOX HSD17B10 1503/4885MEN1 4623/4885MAPT 4766/4885
US-20260000322-A1 DETECTION OF CHANGES IN PATIENT HEALTH BASED ON GLUCOSE DATA SLC5A2, SLC5A1, GLP1R HSD17B10 2405/4885MEN1 215/4885MAPT 2136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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